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Researchers one step closer to blood test which diagnoses most aggressive brain tumour

By January 21, 2022No Comments

University of Sussex researchers have identified distinctive biomarkers within patient blood samples which could indicate Glioblastoma. As the biomarkers were identified in extracellular vesicles, diagnosis through liquid biopsy could prove to be a viable option. This is important as a biopsy would be a faster and less invasive alternative to current diagnostic methods.

Glioblastoma is the most common high grade brain tumour diagnosed in UK adults, with the disease affecting more than 11,000 people each year. It can spread exceptionally quickly, meaning that faster diagnosis – as proposed here – would prove to be a game-changing discovery for thousands of sufferers.

The researchers hope to conduct further research into the clinical value of their findings, by analysing blood samples of a larger cohort of Glioblastoma patients obtained from Genomics England.

Georgios Giamas, Professor of Cancer Cell Signalling at the University of Sussex and one of the leading researchers, said:

“A growing body of research is looking into the possibility of developing liquid biopsies which would afford timely and non-invasive assessment of the disease in patients, starting from just a small sample of blood.

“Our study, which effectively does this in a small patient group, is a major step forward in the development of an accurate, non-invasive and time-saving diagnosis method.”